Whole-Genome Sequence of Livestock-Associated ST398 Methicillin-Resistant Staphylococcus aureus Isolated from Humans in Canada.
Dec 2012
Golding GR, Bryden L, Levett PN, McDonald RR, Wong A, Graham MR, Tyler S, Van Domselaar G, Mabon P, Kent H,Butaye P, Smith TC, Kadlec K, Schwarz S, Weese SJ, Mulvey MR.
Source
National Microbiology Laboratory, Winnipeg, Manitoba, Canada.
Abstract
Despite reports of high colonization rates of ST398 livestock-associated methicillin-resistant Staphylococcus aureus(LA-MRSA) among pigs and pig farmers, the incidence of LA-MRSA infection in the general population in Canada appears to be rare in comparison to that in some European countries. In this study, the complete genome sequence of a Canadian representative LA-MRSA isolate (08BA02176) from a human postoperative surgical site infection was acquired and compared to the sequenced genome of an LA-MRSA isolate (S0385) from Europe to identify genetic traits that may explain differences in the success of these particular strains in some locales.